Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691254 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1GAAVNN1MAPT | |
| SCHEMBL5384366 | 0.85 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1GAAVNN1MAPT | |
| SCHEMBL26750873 | 0.78 | F2 (0.40) | ALDH1A1L3MBTL1GAAVNN1MAPT | |
| SCHEMBL22557054 | 0.78 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1GAAVNN1MAPT | |
| SCHEMBL7451536 | 0.77 | PDCD1 (0.53) | ALDH1A1L3MBTL1GAAMAPTGPR35 | |
| SCHEMBL7451541 | 0.77 | PDCD1 (0.53) | ALDH1A1L3MBTL1GAAMAPTGPR35 | |
| SCHEMBL29896891 | 0.75 | CYP11B1 (0.49) | ALDH1A1GAAVNN1MAPTCNR2 | |
| SCHEMBL586822 | 0.75 | CYP11B1 (0.49) | ALDH1A1GAAVNN1MAPTCNR2 | |
| SCHEMBL14012595 | 0.75 | CYP11B1 (0.49) | ALDH1A1GAAVNN1MAPTCNR2 | |
| SCHEMBL14393663 | 0.75 | VNN1 (0.39) | GAAVNN1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399627-B1 | ANTICOAGULANTS; PROTHROMINASE, SERINE PROTEASE INHIBITOR; ACRYLAMIDE DERIVATIVES | COR THERAPEUTICS, INC. | 2002-06-04 | — | — | US | disclosed |
| EP-1159264-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000047554-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2000-08-17 | — | — | WO | disclosed |