Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695556 | 0.89 | KDM4E (0.75) | KDM4EMAPK1RAD52POLBIKBKB | |
| SCHEMBL9208673 | 0.81 | SOD1 (0.56) | KDM4EMAPK1RAD52POLBKMT2A | |
| SCHEMBL12199181 | 0.75 | KDM4E (1.00) | KDM4EMAPK1RAD52POLBKMT2A | |
| SCHEMBL9207716 | 0.74 | RAD52 (0.44) | KDM4EMAPK1RAD52POLBKMT2A | |
| SCHEMBL7695822 | 0.74 | KDM4E (0.50) | KDM4EMAPK1POLBIKBKBCHUK | |
| SCHEMBL7694581 | 0.71 | SOD1 (0.74) | KDM4EMAPK1POLBKMT2AMEN1 | |
| SCHEMBL4848300 | 0.70 | POLB (0.54) | KDM4EMAPK1RAD52POLBKMT2A | |
| SCHEMBL7330423 | 0.69 | KMT2A (0.67) | KDM4EMAPK1RAD52POLBKMT2A | |
| SCHEMBL28272261 | 0.69 | KDM4E (0.66) | KDM4EMAPK1RAD52POLBIKBKB | |
| SCHEMBL7699335 | 0.68 | ACP1 (0.55) | KDM4EKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |