Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 4/20 | 0.39 |
| ▸ | CHUK | O15111 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28842236 | 0.80 | KDM4E (0.47) | KDM4EMAPK1UTS2RPOLBELANE | |
| SCHEMBL7695991 | 0.78 | MAPT (0.48) | KDM4EMAPK1POLBALDH1A1MAPT | |
| SCHEMBL7695556 | 0.77 | KDM4E (0.75) | KDM4EMAPK1NQO2CYP2C19POLB | |
| SCHEMBL7691825 | 0.76 | JAK2 (0.46) | MAPK1MAPTLMNAHPGDHTT | |
| SCHEMBL7691871 | 0.74 | KDM4E (0.59) | KDM4EMAPK1NQO2POLBIKBKB | |
| SCHEMBL4353261 | 0.72 | MAP4K4 (0.54) | KDM4EMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7699335 | 0.70 | ACP1 (0.55) | KDM4ECYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL4860036 | 0.69 | ACP1 (0.74) | KDM4EMAPK1POLBALDH1A1MAPT | |
| SCHEMBL28798228 | 0.69 | PCSK9 (0.56) | KDM4EUTS2RCYP1A2CYP2C8CYP2C9 | |
| SCHEMBL1548538 | 0.67 | ALDH1A1 (0.56) | MAPK1CYP1A2CYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |