Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 3/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RXRG | P48443 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828378 | 0.98 | FFAR4 (0.56) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL7698029 | 0.97 | FFAR4 (0.55) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL27697415 | 0.95 | RXRB (0.55) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL2728852 | 0.90 | RXRB (0.67) | RXRBRXRARXRGFFAR4ALDH1A1 | |
| SCHEMBL11111979 | 0.88 | RXRB (0.64) | RXRBRXRARXRGFFAR4ALDH1A1 | |
| SCHEMBL28813907 | 0.87 | RXRB (0.46) | RXRBRXRARXRGFFAR4SMN1; SMN2 | |
| SCHEMBL7535153 | 0.83 | FFAR4 (0.50) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL31512087 | 0.83 | FFAR4 (0.50) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL1115123 | 0.83 | CYP1A2 (0.56) | RXRBRXRARXRGFFAR4CYP1A2 | |
| SCHEMBL20680969 | 0.82 | RXRA (0.57) | RXRBRXRARXRGFFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096377-A1 | PYRROLE COMPOUND | 第一三共株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |
| WO-2002024630-A1 | PHARMACEUTICAL COMPOUNDS USEFUL AS MODULATORS OF ENDOCANNABINOID-MEDIATED RESPONSE | ELI LILLY AND COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |
| EP-0010347-A1 | Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |