SCHEMBL11111979

SCHEMBL11111979

O=C(O)CCc1ccc2c(c1)CCCC2

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRB P28702 5/20 0.64
RXRA P19793 4/20 0.64
RXRG P48443 4/20 0.64
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
ALDH1A1 P00352 2/20 0.51
FFAR1 O14842 3/20 0.50
KEAP1 Q14145 1/20 0.48
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
KDM4E B2RXH2 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
FFAR4 Q5NUL3 2/20 0.46
CYP26A1 O43174 1/20 0.44
CYP26B1 Q9NR63 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728852 0.98 RXRB (0.67) RXRBRXRARXRGALOX15TSHR
SCHEMBL20680969 0.94 RXRA (0.57) RXRBRXRARXRGALOX15TSHR
SCHEMBL30263704 0.94 RXRA (0.57) RXRBRXRARXRGALOX15TSHR
SCHEMBL7828378 0.89 FFAR4 (0.56) RXRBRXRARXRGALOX15TSHR
SCHEMBL21810616 0.89 RXRB (0.53) RXRBRXRARXRGALOX15TSHR
SCHEMBL7698029 0.88 FFAR4 (0.55) RXRBRXRARXRGALOX15TSHR
SCHEMBL7691902 0.88 RXRB (0.56) RXRBRXRARXRGALOX15TSHR
SCHEMBL9540541 0.87 RXRB (0.56) RXRBRXRARXRGALOX15TSHR
SCHEMBL27697415 0.86 RXRB (0.55) RXRBRXRARXRGALOX15TSHR
Hydrochloric Acid SCHEMBL20509927 0.85 RXRA (0.50) RXRBRXRARXRGFFAR1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115252615-B Pharmaceutical composition containing fangchinoline-7-propionate and PARP-1 inhibitor 重庆医药高等专科学校 2023-10-24 CN claimed
EP-0039025-B1 DERIVATIVES OF ARYL KETONES AS SENSITIZERS OF PHOTOPOLYMERIZABLE COMPOUNDS FOR THE VISIBLE SPECTRAL RANGE, AND PHOTOPOLYMERIZABLE COMPOSITIONS COMPRISING THE SAID SENSITIZERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
US-4351893-A TRIARYLIMIDAZOLE DIMER INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-28 US disclosed
EP-0039025-A1 Derivatives of aryl ketones as sensitizers of photopolymerizable compounds for the visible spectral range, and photopolymerizable compositions comprising the said sensitizers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-04 EP disclosed