Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.65 |
| ▸ | KDM4A | O75164 | 2/20 | 0.65 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.65 |
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | KDM6A | O15550 | 1/20 | 0.56 |
| ▸ | TET3 | O43151 | 1/20 | 0.56 |
| ▸ | KDM4B | O94953 | 1/20 | 0.56 |
| ▸ | KDM5C | P41229 | 1/20 | 0.56 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.56 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.56 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466724 | 1.00 | KDM4E (0.65) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL11261836 | 0.86 | KDM4E (0.75) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL69905 | 0.85 | KDM4E (0.74) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL30380500 | 0.84 | KDM4E (0.66) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL27642757 | 0.84 | KDM4E (0.50) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL23812284 | 0.81 | NR4A2 (0.54) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL3526280 | 0.81 | PSMD14 (0.54) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL5762503 | 0.81 | KDM4E (0.54) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL17047336 | 0.81 | KDM4E (0.56) | KDM4EL3MBTL1KDM4AEGLN1RAB9A | |
| SCHEMBL31547885 | 0.81 | KDM4E (0.56) | KDM4EL3MBTL1KDM4AEGLN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234220-B2 | Immunomodulatory compounds | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| US-20230322721-A1 | TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS | UNIVERSITY OF OULU (FI) | 2023-10-12 | — | — | US | disclosed |
| US-20230322721-A1 | TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS | UNIVERSITY OF OULU (FI) | 2023-10-12 | — | — | US | disclosed |
| CN-116134026-A | Triazole derivatives and their use as tankyrase inhibitors | 奥斯陆大学国家医院 | 2023-05-16 | — | — | CN | disclosed |
| WO-2022008896-A1 | TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS. | GOLDING, LOUISE (GB) | 2022-01-13 | — | — | WO | disclosed |
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| CN-113166100-A | Immunomodulatory compounds | 达纳-法伯癌症研究所有限公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3814330-A1 | IMMUNOMODULATORY COMPOUNDS | Dana-Farber Cancer Institute, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322721-A1 | TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS | CBR3, GBA3, TECR | KDM4E 3349/4885L3MBTL1 2039/4885KDM4A 3695/4885 |
| US-20210284624-A1 | IMMUNOMODULATORY COMPOUNDS | CRBN, CD47, CD58 | KDM4E 2386/4885L3MBTL1 3521/4885KDM4A 2766/4885 |
| US-12234220-B2 | Immunomodulatory compounds | CRBN, CD47, CD58 | KDM4E 2386/4885L3MBTL1 3521/4885KDM4A 2766/4885 |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN1B, SCN1A, SCN2B | KDM4E 1141/4885L3MBTL1 3351/4885KDM4A 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.