SCHEMBL7692292

SCHEMBL7692292

COCCN(C)C(=O)COc1cc(-c2c(CCl)[nH]c(C(F)(F)F)c2CCl)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.32
ROCK1 Q13464 1/20 0.32
LRRK2 Q5S007 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7688622 0.91 ROCK2 (0.32) ROCK2ROCK1MEN1KMT2APDK2
SCHEMBL7695029 0.88 PDCD1 (0.34) ROCK2ROCK1
SCHEMBL7695699 0.86 ROCK2 (0.32) ROCK2ROCK1MEN1KMT2A
SCHEMBL7694994 0.83 HPGD (0.46) ROCK2ROCK1
SCHEMBL7693096 0.82 ROCK2 (0.31) ROCK2ROCK1
SCHEMBL7694752 0.81 ROCK2 (0.34) ROCK2ROCK1
SCHEMBL7687816 0.78 BACE1 (0.36) ROCK2ROCK1
SCHEMBL7693799 0.78 GAA (0.44) ROCK2ROCK1MEN1KMT2A
SCHEMBL7696823 0.78 PDCD1 (0.33) ROCK2ROCK1
SCHEMBL7693645 0.77 ROCK2 (0.34) ROCK2ROCK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002070476-A1 PHENYLPYRROLES WITH A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2002-09-12 WO claimed
WO-2002070476-A1 PHENYLPYRROLES WITH A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2002-09-12 WO disclosed