Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688614 | 0.90 | HPGD (0.45) | HPGDTSHRLMNANPC1RAB9A | |
| SCHEMBL7694752 | 0.87 | ROCK2 (0.34) | LMNANPC1RAB9ASMN1; SMN2ROCK2 | |
| SCHEMBL7693645 | 0.87 | ROCK2 (0.34) | HPGDTSHRLMNANPC1RAB9A | |
| SCHEMBL7693799 | 0.86 | GAA (0.44) | HPGDTSHRLMNANPC1RAB9A | |
| SCHEMBL7693788 | 0.85 | RAB9A (0.45) | HPGDTSHRLMNANPC1RAB9A | |
| SCHEMBL7694751 | 0.84 | FAAH (0.38) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL7692292 | 0.83 | ROCK2 (0.32) | ROCK2ROCK1 | |
| SCHEMBL7693096 | 0.83 | ROCK2 (0.31) | ROCK2ROCK1 | |
| SCHEMBL7695029 | 0.81 | PDCD1 (0.34) | LMNAROCK2ROCK1 | |
| SCHEMBL7687816 | 0.79 | BACE1 (0.36) | HPGDROCK2ROCK1GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070476-A1 | PHENYLPYRROLES WITH A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2002-09-12 | — | — | WO | disclosed |