Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693830 | 0.81 | NPC1 (0.52) | NPC1RAB9ASMYD3HPGDATM | |
| SCHEMBL6436909 | 0.80 | DGAT2 (0.50) | DGAT2RAB9ACSNK2A2CLK2CSNK2B | |
| SCHEMBL8866585 | 0.77 | SMYD3 (0.46) | DGAT2SMYD3PTPRCMAPTSMN1; SMN2 | |
| SCHEMBL5628818 | 0.76 | CYP1A2 (0.54) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22972454 | 0.76 | CSNK2A2 (0.48) | NPC1RAB9ASMYD3CSNK2A2CSNK2B | |
| SCHEMBL6433846 | 0.75 | DGAT2 (0.47) | DGAT2RAB9ACSNK2A2CLK2CSNK2B | |
| SCHEMBL24725139 | 0.75 | SMYD3 (0.46) | NPC1RAB9ASMYD3HPGDMAPT | |
| SCHEMBL22972033 | 0.74 | SMYD3 (0.48) | NPC1RAB9ASMYD3HPGDMAPT | |
| SCHEMBL2173115 | 0.74 | PLK1 (0.52) | NPC1RAB9ASMYD3SMN1; SMN2KMT2A | |
| SCHEMBL21201145 | 0.74 | CSNK2A2 (0.50) | NPC1RAB9ASMYD3CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |