SCHEMBL769262

SCHEMBL769262

O=P(O)(O)O[C@H]1C(Nc2ncccn2)O[C@H](CO)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.45
MAPT P10636 1/20 0.39
CDA P32320 1/20 0.39
FGF1 P05230 1/20 0.38
FGF2 P09038 1/20 0.38
VEGFA P15692 1/20 0.38
HPSE Q9Y251 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263892 0.82 ADORA1 (0.41) ADORA1
SCHEMBL4875722 0.80 NPC1 (0.49) MAPTCDA
SCHEMBL15955793 0.80 NPC1 (0.49) MAPTCDA
SCHEMBL639417 0.77 ADORA1 (0.42) ADORA1
SCHEMBL379657 0.76 ADORA1 (0.41) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL5245060 0.75 ADORA1 (0.38) ADORA1
SCHEMBL25084035 0.74 IGF2R (0.41)
SCHEMBL860142 0.73 ADORA1 (0.37) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL3691849 0.73 ADORA1 (0.37) ADORA1
SCHEMBL574712 0.73 ADORA1 (0.39) ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070881-A1 Bacillus licheniformis chromosome NOVOZYMES A/S (DK) 2012-03-22 US disclosed