SCHEMBL379657

SCHEMBL379657

O=C(O)c1ccccc1NC1O[C@H](CO)[C@@H](O)[C@H]1OP(=O)(O)O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.41
FGF1 P05230 1/20 0.40
FGF2 P09038 1/20 0.40
VEGFA P15692 1/20 0.40
HPSE Q9Y251 1/20 0.40
LGALS9 O00182 1/20 0.39
LGALS1 P09382 1/20 0.39
LGALS3 P17931 1/20 0.39
LGALS7; LGALS7B P47929 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290451 0.83 SLC5A2 (0.53)
SCHEMBL29508765 0.78 FBP1 (0.48)
SCHEMBL769912 0.78 FBP1 (0.48)
SCHEMBL14742691 0.78 FBP1 (0.48)
SCHEMBL769262 0.76 ADORA1 (0.45) ADORA1FGF1FGF2VEGFAHPSE
Pyrophosphoric Acid SCHEMBL14742591 0.76 FBP1 (0.45)
SCHEMBL860142 0.73 ADORA1 (0.37) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL783243 0.72 LGALS8 (0.41) ADORA1
SCHEMBL10773805 0.70 SLC5A1 (0.44) FGF1FGF2VEGFAHPSE
SCHEMBL10788242 0.70 SLC5A1 (0.44) FGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014217-A1 COMPOSITIONS AND METHODS FOR BACTERIOPHAGE INFECTION OF STAPHYLOCOCCUS BACTERIA WISCONSIN ALUMNI RES FOUND (US) 2026-01-15 US disclosed
US-12416015-B2 Multiplex production and barcoding of genetically engineered cells THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-09-16 US disclosed
US-20250179576-A1 MICROBIAL SIGNATURES OF AUTISM SPECTRUM DISORDER PITON THERAPEUTICS, INC. (US) 2025-06-05 US disclosed
CN-115851688-B TrpCF mutant and application thereof 胡丹 2025-04-18 CN disclosed
WO-2025042804-A1 RECOMBINANT PRODUCTION OF CYCLIC DINUCLEOTIDES UNIVERSITY OF HOUSTON SYSTEM (US) 2025-02-27 WO disclosed
US-20240368535-A1 BURDEN-ADDICTED PRODUCTION STRAINS ENDURO GENETICS APS (DK) 2024-11-07 US disclosed
US-20240360466-A1 ELEVATED RESISTANCE TO INSECTS AND PLANT PATHOGENS WITHOUT COMPROMISING SEED PRODUCTION BOARD OF TRUSTEES OF OMICHIGAN STATE UNIVERSITY 2024-10-31 US disclosed
WO-2023225667-A2 RECOMBINANT BACTERIA FOR PRODUCTION OF INDOLE-3-ACETIC ACID (IAA) AND USES THEREOF SYNLOGIC OPERATING COMPANY, INC. (US) 2023-11-23 WO disclosed
US-20230172997-A1 RECOMBINANT BACTERIA FOR PRODUCTION OF INDOLE-3-ACETIC ACID (IAA) AND USES THEREOF SYNLOGIC OPERATING COMPANY, INC. 2023-06-08 US disclosed
CN-109423468-B Method for increasing yield of compound and derivative thereof in aromatic amino acid biosynthesis pathway 中国科学院微生物研究所 2022-12-20 CN disclosed
WO-2001039777-A1 COMPOUNDS SPECIFIC TO ADENOSINE A1 A2A, AND A3 RECEPTORS AND USES THEREOF OSI PHARMACEUTICALS, INC. (US) 2001-06-07 WO disclosed
EP-1082120-A1 PYRROLO[2,3d]PYRIMIDINE COMPOSITIONS AND THEIR USE OSI Pharmaceuticals, Inc. (US) 2001-03-14 EP disclosed
WO-1999063099-A1 FUNCTIONAL EXPRESSION OF ADENOSINE RECEPTORS IN YEAST CADUS PHARMACEUTICAL CORPORATION (US) 1999-12-09 WO disclosed
WO-1999062518-A1 PYRROLO[2,3d]PYRIMIDINE COMPOSITIONS AND THEIR USE OSI PHARMACEUTICALS, INC. (US) 1999-12-09 WO disclosed
EP-0698218-B1 LABELLED CARBOHYDRATES AND THEIR USE IN ASSAYS OXFORD GLYCOSCIENCES UK LTD (GB) 1999-10-27 EP disclosed
WO-1999049013-A2 TRYPTOPHAN BIOSYNTHETIC ENZYMES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-30 WO disclosed
US-5747347-A DISTINGUISHING BETWEEN CARBOHYDRATES IN MIXTURE BY LABELLING AT REDUCING TERMINAL WITH HYDROPHILIC FLUORESCENT MOIETY, SEPARATING BY DETECTING LABEL OXFORD GLYCOSYSTEMS LTD. (GB) 1998-05-05 US disclosed
EP-0698218-A1 LABELLED CARBOHYDRATES AND THEIR USE IN ASSAYS Oxford GlycoSciences (UK) Limited (GB) 1996-02-28 EP disclosed
WO-1994028423-A1 LABELLED CARBOHYDRATES AND THEIR USE IN ASSAYS OXFORD GLYCOSYSTEMS LTD. (GB) 1994-12-08 WO disclosed
EP-0154133-B1 PLASMIDIC EXPRESSION VEHICLES, AND METHOD OF PRODUCING A POLYPEPTIDE THEREWITH GENENTECH, INC. (US) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014217-A1 COMPOSITIONS AND METHODS FOR BACTERIOPHAGE INFECTION OF STAPHYLOCOCCUS BACTERIA UPF1, POLL, O60361 ADORA1 2521/4885FGF1 1411/4885FGF2 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.