Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768889 | 0.99 | CHRM2 (0.39) | CHRM2MCHR1HDAC6HRH3TRPV4 | |
| SCHEMBL768439 | 0.95 | CHRM2 (0.39) | CHRM2MCHR1HDAC6HRH3TRPV4 | |
| SCHEMBL768447 | 0.94 | CHRM2 (0.35) | CHRM2MCHR1HDAC6HRH3CCR2 | |
| SCHEMBL769140 | 0.93 | CHRM2 (0.36) | CHRM2MCHR1HRH3CCR2CARM1 | |
| SCHEMBL768927 | 0.93 | DRD2 (0.36) | CHRM2MCHR1HRH3CCR2NPC1 | |
| SCHEMBL767545 | 0.91 | CHRM2 (0.39) | CHRM2MCHR1HDAC6HRH3TRPV4 | |
| Hydrochloric Acid SCHEMBL768546 | 0.91 | CCR2 (0.42) | CCR2HTR1ADRD2 | |
| SCHEMBL768358 | 0.91 | HDAC6 (0.38) | CHRM2MCHR1HDAC6HRH3CCR2 | |
| SCHEMBL768708 | 0.91 | CHRM2 (0.39) | CHRM2MCHR1HDAC6HRH3TRPV4 | |
| SCHEMBL769370 | 0.90 | HDAC6 (0.33) | CHRM2MCHR1HDAC6HRH3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | CHRM2 2/4885MCHR1 239/4885HDAC6 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.