Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996732 | 0.88 | CTSK (0.61) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL30902907 | 0.87 | MAPT (0.65) | KLK7KLK5MAPTCPB1CPB2 | |
| SCHEMBL23420126 | 0.85 | MAPT (0.63) | KLK7KLK5MAPTCPB1CPB2 | |
| SCHEMBL12148814 | 0.85 | MAPT (0.62) | KLK7KLK5MAPTCPB1CPB2 | |
| SCHEMBL30902797 | 0.85 | MAPT (0.62) | KLK7KLK5MAPTCPB1CPB2 | |
| SCHEMBL5779877 | 0.85 | KLK7 (0.52) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL20542949 | 0.85 | SIRT2 (0.65) | KLK7KLK5MAPT | |
| SCHEMBL20543102 | 0.85 | SIRT2 (0.65) | KLK7KLK5MAPT | |
| SCHEMBL20542807 | 0.85 | SIRT2 (0.65) | KLK7KLK5MAPT | |
| SCHEMBL20542810 | 0.85 | SIRT2 (0.65) | KLK7KLK5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026697-A2 | AROMATIC DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR, INC. (CA) | 2002-04-04 | — | — | WO | disclosed |