Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ITGAL | P20701 | 7/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459439 | 0.88 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10459440 | 0.88 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL13879634 | 0.81 | RAB9A (0.73) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10458324 | 0.80 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10458323 | 0.80 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL20866524 | 0.78 | TRPV1 (0.72) | RAB9ANPC1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2484738 | 0.78 | TRPV1 (0.72) | RAB9ANPC1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL23388475 | 0.76 | RAB9A (0.66) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL14441234 | 0.76 | KDM4E (0.87) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL20866523 | 0.75 | KDM4E (1.00) | RAB9ANPC1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |