Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ITGAL | P20701 | 9/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 8/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879635 | 0.88 | ALDH1A1 (0.56) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10459440 | 0.84 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10459439 | 0.84 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL7693060 | 0.81 | RAB9A (0.78) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL19508587 | 0.80 | HSD17B3 (0.54) | RAB9ANPC1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13879638 | 0.80 | NPC1 (0.62) | RAB9ANPC1TDP1ITGALALDH1A1 | |
| SCHEMBL13879639 | 0.78 | KDM4E (0.64) | ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL10458324 | 0.77 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL10458323 | 0.77 | RAB9A (1.00) | RAB9ANPC1TDP1L3MBTL1ITGAL | |
| SCHEMBL13879636 | 0.77 | NPC1 (0.44) | RAB9ANPC1TDP1ITGALITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| WO-2007047146-A2 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | RAB9A 3148/4885NPC1 680/4885TDP1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.