Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622408 | 0.83 | LMNA (0.40) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL17853361 | 0.83 | LMNA (0.40) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL1025592 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL4762440 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL22419975 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL25000888 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL21166124 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL11344935 | 0.79 | LMNA (0.42) | ALDH1A1HPGDSMN1; SMN2LMNAAPAF1 | |
| SCHEMBL5258626 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL2764555 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199525-A1 | METHOD FOR ASYMMETRICALLY CATALYZED SYNTHESIS OF NITROPYRAZOLE AMIDE COMPOUND | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2017-08-02 | — | — | EP | disclosed |
| WO-2002059097-A1 | NOVEL GD(III) LIGANDS WITH BI- AND BIS-AZOLIC STRUCTURES | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2002-08-01 | — | — | WO | disclosed |
| US-4505920-A | Certain N-substituted-4-aryl-3,5-pyridine dicarboxylates and their antihypertensive use | USV PHARMACEUTICAL CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |