Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027259 | 0.79 | MAPT (0.41) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL8250805 | 0.76 | IDO1 (0.40) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL10061641 | 0.76 | NOS1 (0.44) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL23177788 | 0.74 | IDO1 (0.39) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL14042674 | 0.73 | ALDH1A1 (0.58) | GAAMAPTHTTIDO1ALDH1A1 | |
| SCHEMBL1467075 | 0.72 | PRKCI (0.42) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL30573342 | 0.72 | PRKCI (0.42) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL10079185 | 0.70 | TAAR1 (0.43) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL12844067 | 0.70 | TAAR1 (0.38) | GAAMAPTTSHRMAPK1HTT | |
| SCHEMBL4525352 | 0.69 | SLC6A4 (0.47) | GAAMAPTALDH1A1PRKCIACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144577-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |