Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695408 | 0.91 | ALDH1A1 (0.57) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL547028 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6689065 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL7055244 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6688605 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6691797 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6689479 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6696712 | 0.78 | MEN1 (0.46) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL22444389 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL6690619 | 0.76 | MEN1 (0.45) | ALDH1A1TDP1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |