Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057039 | 0.85 | CNR2 (0.46) | CNR2P2RX7BRD9BRD4KMT2A | |
| SCHEMBL7253920 | 0.83 | CNR2 (0.44) | CNR2P2RX7BRD9BRD4KMT2A | |
| SCHEMBL6831525 | 0.74 | ALDH1A1 (0.42) | CNR2CRHBPCRHR2KMT2AALDH1A1 | |
| SCHEMBL7055809 | 0.74 | CNR2 (0.42) | CNR2P2RX7CA12CA1CA7 | |
| SCHEMBL6834321 | 0.69 | CNR2 (0.38) | CNR2P2RX7BRD9BRD4ALDH1A1 | |
| SCHEMBL7056759 | 0.68 | TYR (0.37) | CNR2ALDH1A1 | |
| SCHEMBL25833918 | 0.68 | CNR2 (0.38) | CNR2BRD9KMT2AALDH1A1MEN1 | |
| SCHEMBL20905421 | 0.68 | CNR2 (0.44) | CNR2P2RX7BRD4ALDH1A1DRD2 | |
| SCHEMBL22857998 | 0.66 | IRAK4 (0.45) | CNR2P2RX7BRD9BRD4GSK3B | |
| SCHEMBL21868962 | 0.64 | CNR2 (0.36) | CNR2CRHBPCRHR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004417-A1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 4-AMINO-3-HYDROXYPYRROLE-2-CARBOXYLIC ACID | PHARMACIA CORPORAION (US) | 2002-01-17 | — | — | WO | disclosed |