SCHEMBL7055809

SCHEMBL7055809

CCc1c(NC(=O)OC(C)(C)C)cn(C)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.42
BRD9 Q9H8M2 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
MAPK14 Q16539 1/20 0.34
BRD4 O60885 1/20 0.33
P2RX7 Q99572 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
CYP17A1 P05093 2/20 0.32
ACSS2 Q9NR19 1/20 0.32
GSK3B P49841 1/20 0.32
DYRK1A Q13627 1/20 0.32
DRD2 P14416 1/20 0.32
PTPN11 Q06124 1/20 0.32
ELANE P08246 1/20 0.32
MAPT P10636 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21435756 0.83 MEN1 (0.42) CNR2MAPTCA12IDO1RXFP1
SCHEMBL6834321 0.80 CNR2 (0.38) CNR2BRD9BRD4P2RX7GSK3B
SCHEMBL6831525 0.74 ALDH1A1 (0.42) CNR2MAPT
SCHEMBL7693294 0.74 CNR2 (0.47) CNR2BRD9PTGDR2MAPK14BRD4
SCHEMBL21868962 0.74 CNR2 (0.36) CNR2MAPT
SCHEMBL4050633 0.72 CNR2 (0.38) CNR2BRD9PTGDR2PPARGPPARA
SCHEMBL6835329 0.72 MKNK2 (0.41) CNR2MAPT
SCHEMBL7057039 0.72 CNR2 (0.46) CNR2BRD9BRD4P2RX7PPARG
SCHEMBL14271848 0.71 APOBEC3A (0.40) CNR2CYP17A1DRD2MAPTRXFP1
SCHEMBL6181078 0.70 RXFP1 (0.38) CNR2BRD9PTGDR2BRD4P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003020877-A2 STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES PHARMACIA CORPORATION (US) 2003-03-13 WO disclosed