Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14169889 | 0.83 | FNTA (0.46) | XIAPFNTAFNTBPSEN1PSEN2 | |
| SCHEMBL4121598 | 0.76 | ANPEP (0.45) | XIAPFNTAFNTBBCAT2DDB1 | |
| SCHEMBL4122379 | 0.76 | ANPEP (0.45) | XIAPFNTAFNTBBCAT2DDB1 | |
| SCHEMBL4117065 | 0.76 | ANPEP (0.45) | XIAPFNTAFNTBBCAT2DDB1 | |
| SCHEMBL7696137 | 0.75 | FNTA (0.51) | XIAPFNTAFNTBPSEN1PSEN2 | |
| SCHEMBL25408370 | 0.71 | SPPL2A (0.60) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25407546 | 0.71 | SPPL2A (0.60) | XIAPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8514563 | 0.71 | FPR2 (0.64) | FPR1FPR2HDAC8DDB1CRBN | |
| SCHEMBL7694746 | 0.70 | TSHR (0.47) | XIAPHDAC8HTR2CSLC6A3HDAC1 | |
| SCHEMBL3495094 | 0.69 | FPR2 (0.54) | FPR1FPR2HDAC8HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057258-A1 | CYCLO`D!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREOF | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |