Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047690 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL28090595 | 0.81 | PTGDR2 (0.52) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL9097438 | 0.81 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6940724 | 0.80 | MEN1 (0.61) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL2297894 | 0.79 | MEN1 (0.66) | AKR1C3MEN1KMT2AMAPTHPGD | |
| SCHEMBL9164075 | 0.78 | MEN1 (0.60) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL9162780 | 0.77 | MEN1 (0.58) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL6944295 | 0.77 | MEN1 (0.58) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL7424074 | 0.77 | HPGD (0.57) | AKR1C3MEN1KMT2AGAAMAPT | |
| SCHEMBL7059967 | 0.77 | AKR1B1 (0.69) | AKR1C3MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384080-B1 | TREATMENT AND/OR PREVENTION OF CERTAIN CARDIOVASCULAR DISORDERS, UROGENITAL DISORDERS, RESPIRATORY SYSTEM DISORDERS, DISORDERS OF GUT MOTILITY, SEXUAL DISORDERS, DIABETIC COMPLICATIONS, URTICARIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |