Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940724 | 0.88 | MEN1 (0.61) | MEN1KMT2AGAAMAPTCYP1A2 | |
| SCHEMBL28763268 | 0.87 | NPC1 (0.66) | MEN1KMT2AMAPTCYP1A2HPGD | |
| SCHEMBL9162776 | 0.85 | MEN1 (0.54) | MEN1KMT2AGAAMAPTCYP1A2 | |
| SCHEMBL6944295 | 0.85 | MEN1 (0.58) | MEN1KMT2AGAAMAPTCYP1A2 | |
| SCHEMBL9162780 | 0.85 | MEN1 (0.58) | MEN1KMT2AGAAMAPTCYP1A2 | |
| SCHEMBL16043211 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AMAPTHPGDKCNMA1 | |
| SCHEMBL26098852 | 0.82 | CYP1A2 (0.63) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9162784 | 0.81 | HSP90AA1 (0.52) | MEN1KMT2AGAACYP1A2CYP3A4 | |
| SCHEMBL13753896 | 0.80 | L3MBTL1 (0.57) | MEN1KMT2AGAAMAPTCYP1A2 | |
| SCHEMBL13385655 | 0.80 | MEN1 (0.63) | MEN1KMT2AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641311-A1 | NOVEL DIHYDROXYBENZYLAMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023364-A1 | NOVEL DIHYDROXYBENZYLAMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1993-11-25 | — | — | WO | disclosed |