Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7687036 | 0.95 | S100A4 (0.36) | KDM4EALDH1A1SMN1; SMN2PRKCIS100A4 | |
| Sulfuric Acid SCHEMBL7687037 | 0.91 | S100A4 (0.34) | KDM4EALDH1A1SMN1; SMN2PRKCIS100A4 | |
| SCHEMBL7693653 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT | |
| SCHEMBL7690786 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT | |
| SCHEMBL6651190 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT | |
| SCHEMBL9354700 | 0.73 | MAPT (0.33) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15059366 | 0.71 | S100A4 (0.46) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT | |
| SCHEMBL31085219 | 0.69 | S100A4 (0.44) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT | |
| SCHEMBL13481991 | 0.69 | MAPT (0.66) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL18157491 | 0.68 | S100A4 (0.46) | KDM4EALDH1A1SMN1; SMN2S100A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002042285-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-BENZOYLAMINO CHROMAN DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-05-30 | — | — | WO | disclosed |