Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 5/20 | 0.44 |
| ▸ | CLK2 | P49760 | 4/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695414 | 0.78 | MAPK13 (0.42) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL2248104 | 0.76 | NPC1 (0.46) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL2909658 | 0.74 | NPC1 (0.44) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL3641746 | 0.73 | APP (0.62) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL2910487 | 0.73 | NPY5R (0.46) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL28784483 | 0.73 | NPY5R (0.50) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL30844035 | 0.72 | NPC1 (0.51) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL23200198 | 0.71 | NPC1 (0.48) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL30018800 | 0.70 | NPC1 (0.50) | NPC1RAB9ANPY5RHTTLMNA | |
| SCHEMBL5015104 | 0.70 | KCNH3 (0.60) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |