Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 17/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844035 | 0.82 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL1390874 | 0.81 | NFKB1 (0.49) | RECQL | |
| SCHEMBL1391144 | 0.80 | KMT2A (0.65) | RECQLNPC1 | |
| SCHEMBL14869594 | 0.79 | NPC1 (0.49) | RECQLNPC1RAB9A | |
| SCHEMBL1391407 | 0.78 | TRPC5 (0.48) | KCNH3RECQL | |
| SCHEMBL10282666 | 0.76 | APP (0.64) | — | |
| SCHEMBL1391372 | 0.76 | MAPT (0.53) | RECQL | |
| SCHEMBL5015555 | 0.75 | KCNH3 (1.00) | KCNH3RECQL | |
| SCHEMBL5023687 | 0.74 | KCNH3 (0.84) | KCNH3RECQL | |
| SCHEMBL14869685 | 0.74 | NPC1 (0.48) | RECQLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375222-B2 | 2,4,6-Triamino-1,3,5-triazine derivative | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |