Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694683 | 0.96 | MET (0.40) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7689561 | 0.93 | MET (0.40) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7687505 | 0.90 | MET (0.38) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7692473 | 0.90 | MET (0.38) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7692629 | 0.90 | MET (0.36) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7693432 | 0.89 | MET (0.39) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7687452 | 0.88 | ADRB3 (0.38) | METCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7687454 | 0.88 | ADRB3 (0.38) | METCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7686564 | 0.88 | LPAR1 (0.43) | METALDH1A1CYP1A2CYP2D6MAPT | |
| SCHEMBL7694588 | 0.87 | SPHK2 (0.38) | METALDH1A1CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |