Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694683 | 0.94 | MET (0.40) | METKCNH2NR3C1LPAR1LPAR5 | |
| SCHEMBL7693539 | 0.93 | MET (0.39) | METKCNH2NR3C1LPAR1LPAR5 | |
| SCHEMBL7692473 | 0.92 | MET (0.38) | METLPAR1LPAR5ABCB1ALDH1A1 | |
| SCHEMBL7692629 | 0.92 | MET (0.36) | METKCNH2LPAR1LPAR5ABCB1 | |
| SCHEMBL7693432 | 0.92 | MET (0.39) | METLPAR1LPAR5ABCB1ALDH1A1 | |
| SCHEMBL7687505 | 0.91 | MET (0.38) | METLPAR1LPAR5ALDH1A1CYP2C9 | |
| SCHEMBL7686564 | 0.90 | LPAR1 (0.43) | METLPAR1LPAR5ALDH1A1CYP2C9 | |
| SCHEMBL7694588 | 0.90 | SPHK2 (0.38) | METLPAR1LPAR5ALDH1A1CYP2C9 | |
| SCHEMBL7692514 | 0.89 | ADRB1 (0.39) | METLPAR1LPAR5ALDH1A1CYP2C9 | |
| SCHEMBL7698067 | 0.89 | MET (0.43) | METLPAR1LPAR5CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |