Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689181 | 0.85 | ALDH1A1 (0.49) | LMNAALDH1A1MAPK1TSHRMAPT | |
| SCHEMBL5659939 | 0.82 | DHFR (0.42) | ALDH1A1TSHRMEN1SLC22A1DHFR | |
| SCHEMBL7689732 | 0.81 | DHFR (0.51) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL7694315 | 0.79 | MEN1 (0.46) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL5659771 | 0.79 | SMN1; SMN2 (0.52) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL5660937 | 0.77 | DHFR (0.52) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL5657306 | 0.76 | DHFR (0.48) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL5659341 | 0.76 | DHFR (0.48) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL6162999 | 0.76 | DHFR (0.54) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 | |
| SCHEMBL5657190 | 0.75 | MEN1 (0.50) | ALDH1A1TSHRSMN1; SMN2MEN1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002010156-A1 | BENZOFURAN DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ARPIDA AG (CH) | 2002-02-07 | — | — | WO | claimed |
| WO-2002010156-A1 | BENZOFURAN DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ARPIDA AG (CH) | 2002-02-07 | — | — | WO | disclosed |