Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.47 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696555 | 0.88 | MAPK14 (0.46) | MAPK14BRAFMAPK13MAPK12MAPK11 | |
| SCHEMBL7694596 | 0.82 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7696275 | 0.79 | MAPK14 (0.50) | MAPK14BRAFMAPK13MAPK12MAPK11 | |
| SCHEMBL7694545 | 0.78 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL7697090 | 0.78 | MAPK14 (0.38) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL20962200 | 0.76 | MAPK14 (0.59) | MAPK14BRAFMAPK13MAPK12MAPK11 | |
| SCHEMBL7697641 | 0.74 | AURKA (0.54) | — | |
| SCHEMBL7691122 | 0.70 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL1012863 | 0.70 | MAPK14 (0.60) | MAPK14BRAFMAPK13MAPK12MAPK11 | |
| SCHEMBL13990647 | 0.70 | POLB (0.57) | MAPK14NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |