Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | IDH2 | P48735 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691876 | 0.86 | PDGFRB (0.55) | AURKAPDGFRBPDGFRAABCG2 | |
| SCHEMBL7697737 | 0.83 | CTSC (0.45) | AURKAIDH2PDGFRBPDGFRACTSC | |
| SCHEMBL3907717 | 0.83 | MAPT (0.53) | AURKAIDH2PDGFRBPDGFRATHRB | |
| SCHEMBL7697848 | 0.82 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2EGFRKDM4E | |
| SCHEMBL7698400 | 0.81 | IDH2 (0.60) | AURKAIDH2ABCG2EGFRGAA | |
| SCHEMBL7696400 | 0.81 | PDGFRB (0.76) | AURKAPDGFRBPDGFRAABCG2KDM4E | |
| SCHEMBL7699307 | 0.79 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2EGFR | |
| SCHEMBL7699322 | 0.79 | PDGFRB (0.71) | PDGFRBPDGFRAABCG2EGFR | |
| SCHEMBL7691917 | 0.79 | PDGFRB (0.56) | PDGFRBPDGFRAABCG2EGFR | |
| SCHEMBL4214745 | 0.79 | AURKA (0.58) | AURKAIDH2THRBABCG2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |