SCHEMBL7696555 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	16/20	0.46

▸	MAPK13	O15264	7/20	0.42

▸	MAPK12	P53778	6/20	0.41

▸	MAPK11	Q15759	6/20	0.41

▸	KIT	P10721	1/20	0.40

▸	NTRK1	P04629	1/20	0.40

▸	NTRK3	Q16288	1/20	0.40

▸	NTRK2	Q16620	1/20	0.40

▸	MAPK9	P45984	3/20	0.40

▸	BRAF	P15056	2/20	0.40

▸	CDK8	P49336	1/20	0.40

▸	SRC	P12931	1/20	0.39

▸	DDR2	Q16832	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7694076	0.88	MAPK14 (0.47)	MAPK14MAPK13MAPK12MAPK11KIT
SCHEMBL7694596	0.84	MAPK14 (0.56)	MAPK14MAPK13MAPK12MAPK11KIT
SCHEMBL7691122	0.82	MAPK14 (0.50)	MAPK14MAPK13MAPK12MAPK11MAPK9
SCHEMBL7696275	0.80	MAPK14 (0.50)	MAPK14MAPK13MAPK12MAPK11NTRK1
SCHEMBL7694545	0.79	MAPK14 (0.48)	MAPK14MAPK13MAPK12MAPK11KIT
SCHEMBL7697090	0.79	MAPK14 (0.38)	MAPK14MAPK13MAPK12MAPK11DDR2
SCHEMBL7700675	0.76	MAPK14 (0.43)	MAPK14MAPK13MAPK12MAPK11NTRK1
SCHEMBL7697564	0.76	MAPK14 (0.41)	MAPK14MAPK13MAPK12MAPK11NTRK1
SCHEMBL7693923	0.76	MAPK14 (0.45)	MAPK14MAPK13MAPK12MAPK11NTRK1
SCHEMBL7690441	0.76	MAPK14 (0.47)	MAPK14MAPK13MAPK12MAPK11NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2002094796-A2	BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES	AXXIMA PHARMACEUTICALS AG (DE)	2002-11-28	—	—	WO	disclosed