Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703337 | 0.91 | GAA (0.49) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7698748 | 0.87 | KDM4E (0.61) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7703233 | 0.87 | KDM4E (0.73) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7694070 | 0.87 | KDM4E (0.73) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7701004 | 0.85 | KDM4E (0.59) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7698787 | 0.84 | KDM4E (0.58) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7696393 | 0.84 | KDM4E (0.57) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7703322 | 0.84 | KDM4E (0.72) | KDM4EGAARAB9ANPC1ALDH1A1 | |
| SCHEMBL7693982 | 0.82 | NLRP3 (0.44) | KDM4ERAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL7693588 | 0.82 | KDM4E (0.65) | KDM4EGAARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |