Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | WHR1 | P49842 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700056 | 0.89 | ALDH1A1 (0.55) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL30065410 | 0.81 | HPGD (0.64) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL396614 | 0.81 | HPGD (0.64) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL28611035 | 0.80 | HPGD (0.62) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL26317752 | 0.79 | FGFR2 (0.56) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7699246 | 0.78 | KDM4E (0.49) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7693996 | 0.77 | KDM4E (0.51) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL12695592 | 0.77 | BACE1 (0.57) | KDM4EMEN1KMT2AHPGDLMNA | |
| SCHEMBL7697819 | 0.77 | KDM4E (0.51) | KDM4ESMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL7691857 | 0.77 | L3MBTL1 (0.60) | KDM4ESMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002026713-A1 | ANTIPARASITIC COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2002-04-04 | — | — | WO | disclosed |