Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591996 | 0.84 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL5591875 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL2210585 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL21050840 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL2209335 | 0.78 | ALDH1A1 (0.76) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL3583405 | 0.77 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL25418982 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL21136847 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL21050843 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL21050879 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP1A2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748799-B1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5731440-A | Intermediates for producing 5,7-dichloro-4-hydroxyquinoline | ISHIHARA SANGYO KAISHA LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0748799-A1 | PROCESS FOR PRODUCING 5,7-DICHLORO-4-HYDROXYQUINOLINE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |