⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775544 | 0.97 | — | — | |
| SCHEMBL9125694 | 0.90 | — | — | |
| SCHEMBL6932006 | 0.88 | DNM1 (0.47) | — | |
| SCHEMBL9128493 | 0.88 | DNM1 (0.47) | — | |
| Trifluoroacetic Acid SCHEMBL7701845 | 0.79 | ODC1 (0.52) | — | |
| SCHEMBL7694297 | 0.79 | — | — | |
| SCHEMBL10854227 | 0.76 | — | — | |
| SCHEMBL140976 | 0.72 | NFKB1 (0.43) | — | |
| SCHEMBL636982 | 0.72 | — | — | |
| SCHEMBL816414 | 0.72 | NFKB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340770-B1 | COMPLEXES WITH DIAMINE COMPOUNDS WITH DIACIDS | SOOK MYUNG WOMEN'S UNIVERSITY (KR) | 2002-01-22 | — | — | US | claimed |
| US-6340770-B1 | COMPLEXES WITH DIAMINE COMPOUNDS WITH DIACIDS | SOOK MYUNG WOMEN'S UNIVERSITY (KR) | 2002-01-22 | — | — | US | disclosed |
| US-20010051631-A1 | Tricyclic compounds, their production and use | TAKATANI MUNEO (JP) | 2001-12-13 | — | — | US | disclosed |
| US-6251905-B1 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| JP-2000319290-A | NEW PLATINUM (IV) COMPLEX AND ITS PRODUCTION | SOOKMYUNG WOMEN'S UNIV | 2000-11-21 | — | — | JP | disclosed |
| US-5958942-A | HAVING EXCELLENT PDGF-INHIBITING ACTIVITIES, ANTIHYPERTENSIVE ACTIVITIES, ACTIVITIES OF AMELIORATING RENAL DISEASES AND ACTIVITIES OF LOWERING LIPID LEVEL. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0771319-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996002542-A1 | TRICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |