Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696848 | 0.93 | ALDH1A1 (0.49) | MAPTALDH1A1GAAHPGDTDP1 | |
| SCHEMBL7700070 | 0.90 | TP53 (0.49) | MAPTALDH1A1GAAHPGDTP53 | |
| SCHEMBL7698777 | 0.89 | MAPT (0.40) | MAPTALDH1A1GAAHPGDTDP1 | |
| SCHEMBL7697504 | 0.89 | MAPT (0.38) | MAPTALDH1A1GAAHPGDTP53 | |
| SCHEMBL7694774 | 0.87 | MAPT (0.41) | MAPTALDH1A1GAAHPGDTDP1 | |
| SCHEMBL7704672 | 0.85 | MAPT (0.45) | MAPTALDH1A1GAAHPGDTDP1 | |
| SCHEMBL7699872 | 0.85 | ALDH1A1 (0.42) | MAPTALDH1A1TDP1TP53MAPK1 | |
| SCHEMBL7700867 | 0.83 | ALDH1A1 (0.41) | MAPTALDH1A1TDP1TP53MAPK1 | |
| SCHEMBL7696341 | 0.79 | MAPT (0.44) | MAPTALDH1A1GAAHPGDTDP1 | |
| SCHEMBL7704674 | 0.78 | MAPT (0.69) | MAPTALDH1A1GAAHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |