Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700429 | 0.90 | ALDH1A1 (0.45) | MAPTALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL7696341 | 0.89 | MAPT (0.44) | MAPTALDH1A1TDP1GAAHPGD | |
| SCHEMBL7699868 | 0.88 | ALDH1A1 (0.37) | MAPTALDH1A1TDP1TSHRTP53 | |
| SCHEMBL7695041 | 0.88 | TP53 (0.47) | MAPTALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL7696679 | 0.86 | MAPT (0.42) | MAPTALDH1A1TDP1GAAHPGD | |
| SCHEMBL7696676 | 0.86 | TP53 (0.43) | MAPTALDH1A1TDP1TSHRHSD17B10 | |
| SCHEMBL7694366 | 0.85 | MAPT (0.44) | MAPTALDH1A1TDP1GAAHPGD | |
| SCHEMBL7702473 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1TDP1TSHRTP53 | |
| SCHEMBL7700902 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1TDP1HPGDTSHR | |
| SCHEMBL7702583 | 0.82 | POLB (0.42) | MAPTALDH1A1TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |