Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.78 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317692 | 0.88 | PTPN1 (1.00) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6315990 | 0.79 | PTPN1 (0.84) | PTPN1PTPN2PTPRA | |
| SCHEMBL8288834 | 0.77 | PTPN2 (0.65) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7859688 | 0.77 | PTPN1 (0.65) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL6315212 | 0.77 | PTPN1 (1.00) | PTPN1PTPN2KDM4EPTPRA | |
| SCHEMBL28377333 | 0.76 | MEN1 (0.83) | PTPN1PTPN2KDM4EMEN1MAPT | |
| SCHEMBL8288699 | 0.76 | PTPN2 (0.63) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8290859 | 0.76 | KDM4E (0.61) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8288753 | 0.75 | ALDH1A1 (1.00) | PTPN1PTPN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL5506528 | 0.71 | GAA (0.66) | PTPN1PTPN2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410586-B1 | ANTICOAGULANTS; INSULIN RESISTANCE; ANTIALLERGENS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | disclosed |