Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 0.82 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TLR2 | O60603 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290361 | 0.92 | ALDH1A1 (0.86) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL6993515 | 0.81 | GAA (1.00) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL28377356 | 0.78 | MEN1 (0.73) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL20915167 | 0.76 | KMT2A (0.75) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL3924354 | 0.76 | TLR2 (0.72) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL4084442 | 0.76 | KDM4E (0.70) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7719431 | 0.75 | GAA (0.89) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7694395 | 0.75 | PTPN1 (0.78) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL6204125 | 0.75 | LMNA (0.70) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL6317692 | 0.75 | PTPN1 (1.00) | ALDH1A1KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |