Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.53 |
| ▸ | ITGAV | P06756 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA5A | P35218 | 4/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698171 | 1.00 | ITGB3 (0.53) | ITGB3ITGAVF10MMP1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7695123 | 0.96 | ITGB3 (0.50) | ITGB3ITGAVF10MMP1MMP2 | |
| Trifluoroacetic Acid SCHEMBL7699173 | 0.96 | ITGB3 (0.50) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7455662 | 0.89 | ITGB3 (0.52) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7455657 | 0.89 | ITGB3 (0.52) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7455533 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7455523 | 0.89 | ITGB3 (0.51) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7462968 | 0.82 | F10 (0.48) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7465932 | 0.82 | F10 (0.48) | ITGB3ITGAVF10MMP1MMP2 | |
| SCHEMBL7456479 | 0.82 | F10 (0.47) | ITGB3ITGAVF10MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344484-B1 | TREATMENT OF TUMOR GROWTH, METASTASIS, OSTEOPOROSIS, RESTENOSIS, INFLAMMATION, MACULAR DEGENERATION, DIABETIC RETINOPATHY, AND RHEUMATOID ARTHRITIS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-02-05 | — | — | US | claimed |