Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702477 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7700906 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7694406 | 0.87 | ALDH1A1 (0.52) | ALDH1A1KDM4EHTTMAPK1KMT2A | |
| SCHEMBL7695048 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4EHTTHPGDKMT2A | |
| SCHEMBL7695265 | 0.83 | UBE2N (0.56) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7697517 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EHTTKMT2AGAA | |
| SCHEMBL7696767 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7695104 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7701852 | 0.80 | MAPT (0.51) | ALDH1A1KDM4EHTTMAPK1HPGD | |
| SCHEMBL7700945 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EHTTMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |