Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702477 | 0.90 | ALDH1A1 (0.55) | MAPTTP53LMNAKMT2AGAA | |
| SCHEMBL7695048 | 0.83 | ALDH1A1 (0.66) | MAPTTP53LMNAKMT2AALDH1A1 | |
| SCHEMBL7698779 | 0.81 | MAPT (0.56) | MAPTTP53LMNAKMT2AGAA | |
| SCHEMBL7700433 | 0.81 | KMT2A (0.69) | MAPTTP53LMNAKMT2AGAA | |
| SCHEMBL7694406 | 0.81 | ALDH1A1 (0.52) | MAPTTP53KMT2AGAAMEN1 | |
| SCHEMBL7695177 | 0.81 | ALDH1A1 (0.66) | MAPTTP53LMNAKMT2AGAA | |
| SCHEMBL7694568 | 0.80 | ALDH1A1 (0.54) | MAPTTP53KMT2AGAAMEN1 | |
| SCHEMBL7701804 | 0.80 | ALDH1A1 (0.50) | MAPTTP53LMNAKMT2AMEN1 | |
| SCHEMBL7700906 | 0.79 | ALDH1A1 (0.61) | MAPTTP53KMT2AGAAMEN1 | |
| SCHEMBL7695043 | 0.78 | MAPT (0.63) | MAPTTP53KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |