Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512202 | 0.91 | CHRNA3 (0.32) | CHRNB2CHRNA4CHRNB4CHRNA3OPRL1 | |
| SCHEMBL16116173 | 0.91 | CHRNA3 (0.32) | CHRNB2CHRNA4CHRNB4CHRNA3OPRL1 | |
| SCHEMBL17512205 | 0.91 | CHRNA3 (0.32) | CHRNB2CHRNA4CHRNB4CHRNA3OPRL1 | |
| SCHEMBL7701964 | 0.89 | CYP11B1 (0.33) | CYP11B1CYP11B2BACE1USP14 | |
| SCHEMBL16555300 | 0.88 | OPRL1 (0.35) | CYP11B1CYP11B2OPRL1 | |
| SCHEMBL379213 | 0.88 | OPRL1 (0.35) | CYP11B1CYP11B2OPRL1 | |
| SCHEMBL16565846 | 0.88 | OPRL1 (0.35) | CYP11B1CYP11B2OPRL1 | |
| SCHEMBL16565906 | 0.86 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL16554204 | 0.86 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL16565739 | 0.85 | OPRL1 (0.30) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057262-A2 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |