SCHEMBL379213

SCHEMBL379213

N#CC1(c2cncc(Cl)c2)CC2CCC(C1)N2CC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 1/20 0.35
TRPA1 O75762 1/20 0.33
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16555300 1.00 OPRL1 (0.35) OPRL1TRPA1CYP11B1CYP11B2
SCHEMBL16565846 1.00 OPRL1 (0.35) OPRL1TRPA1CYP11B1CYP11B2
SCHEMBL6617204 0.95 TRPA1 (0.34) OPRL1TRPA1
SCHEMBL6996255 0.88 TRPA1 (0.33) TRPA1
SCHEMBL7694965 0.88 CYP11B1 (0.35) OPRL1CYP11B1CYP11B2
SCHEMBL6992532 0.87 TRPA1 (0.32) TRPA1
SCHEMBL6615641 0.87 TRPA1 (0.30) TRPA1
SCHEMBL16565906 0.86 OPRL1 (0.31) OPRL1
SCHEMBL7229023 0.86 OPRL1 (0.35) OPRL1
SCHEMBL16554204 0.86 OPRL1 (0.31) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213168-A1 Pesticidal combination of active agents Bayer CropScience AG (DE) 2010-08-04 EP claimed
US-20100137373-A1 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-06-03 US claimed
EP-2157857-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND Bayer CropScience SA (FR) 2010-03-03 EP claimed
US-20100048497-A1 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) BAYER CROPSCIENCE AG (DE) 2010-02-25 US claimed
US-20100048404-A1 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-02-25 US claimed
EP-2107871-A2 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) Bayer CropScience AG (DE) 2009-10-14 EP claimed
EP-2091327-A2 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND Bayer CropScience SA (FR) 2009-08-26 EP claimed
WO-2008152091-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-12-18 WO claimed
EP-2000029-A1 Insecticide and fungicide active agent combinations Bayer CropScience AG (DE) 2008-12-10 EP claimed
US-20080293566-A1 Active Substance Combinations BAYER CROPSCIENCE AG (DE) 2008-11-27 US claimed
WO-2008071674-A2 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-06-19 WO claimed
WO-2008064778-A2 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) BAYER CROPSCIENCE AG (DE) 2008-06-05 WO claimed
EP-1876897-A2 ACTIVE SUBSTANCE COMBINATIONS Bayer CropScience AG (DE) 2008-01-16 EP claimed
WO-2006114212-A2 COMBINATIONS OF PESTICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO claimed
EP-0944319-A1 INSECTICIDAL COMPOSITIONS AND METHODS ZENECA LIMITED (GB) 1999-09-29 EP claimed
WO-1998023158-A1 INSECTICIDAL COMPOSITIONS AND METHODS ZENECA LIMITED (GB) 1998-06-04 WO claimed
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2025-12-25 US disclosed
EP-3801014-B1 AGROCHEMICAL FORMULATIONS CONTAINING A POLYMERIC CRYSTAL GROWTH INHIBITOR BAYER AG (DE) 2025-08-27 EP disclosed
EP-0828739-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1998-03-18 EP disclosed
WO-1996037494-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1996-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048404-A1 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND AN INSECTICIDE COMPOUND CYP51A1, DDT, ACHE OPRL1 4504/4885TRPA1 2617/4885CYP11B1 339/4885
US-20080293566-A1 Active Substance Combinations AADAC, CHIA, CAT OPRL1 3896/4885TRPA1 148/4885CYP11B1 2424/4885
US-20100048497-A1 INSECTICIDAL ACTIVE INGREDIENT COMBINATIONS (FORMONONETINS + INSECTICIDES) ACHE, ACAT1, CIAPIN1 OPRL1 4501/4885TRPA1 350/4885CYP11B1 435/4885
US-20100137373-A1 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN INSECTICIDE COMPOUND PTMS, STK39, CYP17A1 OPRL1 4657/4885TRPA1 2643/4885CYP11B1 18/4885
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA MAX, SEC62, GHITM OPRL1 4728/4885TRPA1 3721/4885CYP11B1 4787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.