⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8277481 | 0.80 | CA12 (0.36) | — | |
| SCHEMBL15038536 | 0.78 | CA12 (0.50) | — | |
| SCHEMBL8277478 | 0.76 | — | — | |
| SCHEMBL164890 | 0.74 | EHMT2 (0.40) | — | |
| SCHEMBL8013735 | 0.74 | EHMT2 (0.40) | — | |
| SCHEMBL8277479 | 0.74 | MLYCD (0.39) | — | |
| SCHEMBL9481808 | 0.73 | CA12 (0.52) | — | |
| SCHEMBL4512241 | 0.71 | — | — | |
| SCHEMBL8279944 | 0.71 | LMNA (0.63) | — | |
| SCHEMBL4355947 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-20250236609-A1 | VPS34 INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC | 2025-07-24 | — | — | US | disclosed |
| WO-2025129019-A1 | VPS34 INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS, LLC (US) | 2025-06-19 | — | — | WO | disclosed |
| US-11678659-B2 | Use as rodenticides of compounds that inhibit blood coagulation | GULBA DIETRICH (DE) | 2023-06-20 | — | — | US | disclosed |
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| US-10683270-B2 | Cannabinoid receptor mediating compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190193062-A1 | CATALYSTS FOR POLYCARBONATE PRODUCTION | ARAMCO PERFORMANCE MATERIALS LLC | 2019-06-27 | — | — | US | disclosed |
| US-20180022706-A1 | CANNABINOID RECEPTOR MEDIATING COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-01-25 | — | — | US | disclosed |
| US-9765031-B2 | Cannabinoid receptor mediating compounds | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-06-29 | — | — | US | disclosed |
| US-5264448-A | Thioamides, oxazole ring, insecticides, miticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0394043-A1 | An amide compound and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| EP-0008047-B1 | 5(6)-(2-AMINO-5-THIAZOLOYL)BENZIMIDAZOLE-2-CARBAMIC ACID ESTERS AND THEIR SALTS, THEIR PREPARATION AND USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | disclosed |
| US-4386097-A | Benzimidazoles, processes for their preparation and pharmaceutical preparations containing such compounds | CIBA-GEIGY CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |
| US-4297365-A | Benzimidazoles and pharmaceutical preparations containing such compounds | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0008047-A1 | 5(6)-(2-Amino-5-thiazoloyl)benzimidazole-2-carbamic acid esters and their salts, their preparation and use, and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-02-20 | — | — | EP | disclosed |