SCHEMBL7695301

SCHEMBL7695301

O=C(Cl)c1cc(-c2c(CCl)[nH]c(C(F)(F)F)c2CCl)c(F)cc1Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.31
ROCK1 Q13464 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690112 0.83 GYS1 (0.31)
SCHEMBL7693096 0.82 ROCK2 (0.31) ROCK2ROCK1
SCHEMBL7687816 0.82 BACE1 (0.36) ROCK2ROCK1
SCHEMBL7690089 0.82 GAA (0.39)
SCHEMBL7689277 0.81 ROCK2 (0.32) ROCK2ROCK1
SCHEMBL7687932 0.77 GAA (0.31)
SCHEMBL7693702 0.76 ROCK2 (0.30) ROCK2ROCK1
SCHEMBL7694752 0.75 ROCK2 (0.34) ROCK2ROCK1
SCHEMBL7695995 0.75 ROCK2 (0.31) ROCK2ROCK1
SCHEMBL7695029 0.75 PDCD1 (0.34) ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002070476-A1 PHENYLPYRROLES WITH A HERBICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2002-09-12 WO disclosed