Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | KDM5A | P29375 | 2/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.53 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ASPH | Q12797 | 3/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2042821 | 0.83 | KDM4E (0.38) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL28244686 | 0.81 | KDM4E (0.35) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL31000446 | 0.81 | ADORA3 (0.41) | KDM4EKDM5AKDM3AJMJD1CTSHR | |
| SCHEMBL1505808 | 0.77 | KDM4E (0.57) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL19361039 | 0.76 | KDM4E (0.33) | KDM4EKDM5AKDM3AJMJD1CASPH | |
| SCHEMBL27287238 | 0.76 | MAPT (0.45) | KDM4EKDM3AALOX15TSHRALDH1A1 | |
| SCHEMBL163233 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL87765 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL31126262 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 | |
| SCHEMBL3560191 | 0.76 | KDM4E (0.55) | KDM4EKDM5AKDM3AJMJD1CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656406-B | Synthesis method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-114656406-A | Synthetic method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-104003934-A | 6-chlorine-3-fluorine-2-picolinic acid synthesis process | UNIV XIHUA | 2014-08-27 | — | — | CN | claimed |
| WO-2024163382-A2 | 18F-LABELED PET RADIOTRACERS FOR IMAGING MACROPHAGE COLONY STIMULATING FACTOR 1 RECEPTOR | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-08-08 | — | — | WO | disclosed |
| CN-114656406-B | Synthesis method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114656406-B | Synthesis method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114656406-B | Synthesis method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114656406-A | Synthetic method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656406-A | Synthetic method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656406-A | Synthetic method of 2-fluoropyrimidine-4-carboxylic acid | 阿里生物新材料（常州）有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-108473478-A | TBK/IKK inhibitor compounds and uses thereof | 默克专利有限公司 | 2018-08-31 | — | — | CN | disclosed |
| US-6337368-B1 | WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES | KANEKA CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1008383-A1 | LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |