Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268709 | 0.75 | OPRL1 (0.74) | OPRL1OPRM1OPRD1OPRK1USP2 | |
| SCHEMBL14635953 | 0.73 | OPRM1 (0.69) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2640857 | 0.72 | OPRL1 (0.46) | OPRL1CYP2D6ALDH1A1 | |
| SCHEMBL23203155 | 0.71 | OPRL1 (0.46) | OPRL1USP2CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL71724 | 0.68 | NPSR1 (0.57) | OPRL1OPRM1OPRD1OPRK1USP2 | |
| SCHEMBL28176312 | 0.68 | OPRM1 (0.51) | OPRL1OPRM1OPRD1OPRK1USP2 | |
| SCHEMBL15156334 | 0.67 | OPRL1 (0.73) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL6363940 | 0.67 | OPRL1 (0.73) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL6498050 | 0.67 | OPRL1 (0.73) | OPRL1OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL14742155 | 0.66 | CYP3A4 (0.69) | OPRL1OPRM1OPRD1OPRK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012187-A1 | NOVEL PHENYLHETEROAZETIDINES, USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |