Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | DHFR | P00374 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695807 | 0.94 | GAA (0.63) | MAPTGAAALDH1A1ABCB1LMNA | |
| SCHEMBL7697692 | 0.91 | ALDH1A1 (0.70) | MAPTGAAALDH1A1ABCB1LMNA | |
| SCHEMBL7695378 | 0.87 | ALDH1A1 (0.67) | MAPTGAAALDH1A1ABCB1LMNA | |
| SCHEMBL26598049 | 0.84 | DHFR (0.66) | MAPTGAAALDH1A1ABCB1LMNA | |
| SCHEMBL13167285 | 0.81 | GAA (0.75) | MAPTGAAALDH1A1ABCB1LMNA | |
| SCHEMBL10113073 | 0.80 | CA1 (0.74) | ALDH1A1LMNACYP2C9CYP2C19DHFR | |
| SCHEMBL7694783 | 0.79 | ALDH1A1 (0.72) | MAPTGAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7696383 | 0.77 | DHFR (0.74) | ALDH1A1LMNACYP2C9CYP2C19DHFR | |
| SCHEMBL10112932 | 0.77 | ALDH1A1 (0.65) | MAPTGAAALDH1A1LMNACYP2C9 | |
| SCHEMBL7692642 | 0.75 | ALDH1A1 (0.78) | MAPTGAAALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |